Publications

Identification of a specific set of genes predicting obesity before phenotype appearance. Jousse C, Parry L, Cueff G, Brandolini-Bunlon M, Tournayre J, Bruhat A, Maurin AC, Vituret C, Averous J, Muranishi Y, Fafournoux P. iScience. Sous presse

Pre-cachectic changes in amino acid homeostasis precede activation of eIF2α signaling in the liver at the onset of C26 cancer-induced cachexia. Chaouki G, Parry L, Vituret C, Jousse C, Leremboure M, Bourgne C, Mosoni L, Delorme Y, Djelloul-Mazouz M, Hermet J, Averous J, Bruhat A, Combaret L, Taillandier D, Papet I, Bindels LB, Fafournoux P, Maurin AC. iScience. 2025 Feb 14;28(3):112030. doi: 10.1016/j.isci.2025.112030. eCollection 2025 Mar 21. PMID: 40124481

Transcriptomic analysis of human primary T cells after short-term leucine-deprivation and evaluation of kinase GCN2's role in regulating differential gene expression. Dougé A, Cueff G, Keime C, Carraro V, Jousse C, Rouzaire P, Bruhat A. PLoS One. 2025 Feb 18;20(2):e0317505. doi: 10.1371/journal.pone.0317505. eCollection 2025. PMID: 39965008

Structure predictions of MuRF1-UBE2 complexes identify amino acid residues governing interaction selectivity for each MuRF1-E2 pair. Claustre A, Malige M, Macheton M, Combaret L, Lefai E, Fafournoux P, Taillandier D, Henri J, Polge C. FEBS J. 2025 Feb 10. doi: 10.1111/febs.70017. Online ahead of print. PMID: 39930652

Knockout of the Muscle-Specific E3 Ligase MuRF1 Affects Liver Lipid Metabolism upon Dexamethasone Treatment in Mice. Mosoni L, Germond A, Coudy-Gandilhon C, Malige M, Claustre A, Delabrise C, Djelloul-Mazouz M, Delorme Y, Hermet J, Fafournoux P, Combaret L, Polge C, Maurin AC, Taillandier D. ACS Omega. 2024 Oct 31;9(45):45610-45623. doi: 10.1021/acsomega.4c08501. eCollection 2024 Nov 12. PMID: 39554453

Temporal regulation of transgene expression controlled by amino acid availability in human T cells. Dougé A, Vituret C, Carraro V, Parry L, Coudy-Gandilhon C, Lemal R, Combaret L, Maurin A-C, Averous J, Jousse C, Bay J-O, Verrelle P, Fafournoux P, Bruhat A, Rouzaire P. HLA 2024 Jan;103(1):e15252. doi: 10.1111/tan.15252.

Tripartite split-GFP for high throughput screening of small molecules: a powerful strategy for targeting transient/labile interactors like E2-E3 ubiquitination enzymes. Polge C, Cabantous S, Taillandier D. Chembiochem 2023 Dec 13:e202300723. doi: 10.1002/cbic.202300723.

Induction of ATF4-Regulated Atrogenes Is Uncoupled from Muscle Atrophy during Disuse in Halofuginone-Treated Mice and in Hibernating Brown Bears. Cussonneau L, Coudy-Gandilhon C, Deval C, Chaouki G, Djelloul-Mazouz M, Delorme Y, Hermet J, Gauquelin-Koch G, Polge C, Taillandier D, Averous J, Bruhat A, Jousse C, Papet I, Bertile F, Lefai E, Fafournoux P, Maurin A-C, Combaret L. Int J Mol Sci 2022 Dec 30;24(1):621. doi: 10.3390/ijms24010621.

GCN2 upregulates autophagy in response to short-term deprivation of a single essential amino acid. Maurin A-C, Parry L, B’chir W, Carraro V, Coudy-Gandilhon C, Chaouki G, Chaveroux C, Mordier S, Martinie B, Reinhardt V, Jousse C, Bruhat A, Codogno P, Averous J, Fafournoux P. Autophagy Reports 2022, 1:1, 119-142, doi: 10.1080/27694127.2022.2049045.

Activation of the eIF2α-ATF4 Pathway by Chronic Paracetamol Treatment Is Prevented by Dietary Supplementation with Cysteine. Carraro V, Combaret L, Coudy-Gandilhon C, Parry L, Averous J, Maurin A-C, Jousse C, Voyard G, Fafournoux P, Papet I, Bruhat A. Int J Mol Sci 2022 Jun 28;23(13):7196. doi: 10.3390/ijms23137196.

When idiopathic male infertility is rooted in maternal malnutrition during the perinatal period in mice. Muranishi Y, Parry P, Vachette-Dit-Martin M, Saez F, Coudy-Gandilhon C, Sauvanet P, Volle D, Tournayre J, Bottari S, Carpentiero F, Martinez G, Muroňová J, Escoffier J, Bruhat A, Maurin A-C, Averous J, Arnoult C, Fafournoux P, Jousse C. Biol Reprod 2022 Mar 19;106(3):463-476. doi: 10.1093/biolre/ioab222.

UBE2L3, a Partner of MuRF1/TRIM63, Is Involved in the Degradation of Myofibrillar Actin and Myosin. Peris-Moreno D, Malige M, Claustre A, Armani A, Coudy-Gandilhon C, Deval C, Béchet D, Fafournoux P, Sandri M, Combaret L, Taillandier D, Polge C. Cells 2021 Aug 3;10(8):1974. doi: 10.3390/cells10081974.

Concurrent BMP Signaling Maintenance and TGF-β Signaling Inhibition Is a Hallmark of Natural Resistance to Muscle Atrophy in the Hibernating Bear. Cussonneau L, Boyer C, Brun C, Deval C, Loizon E, Meugnier E, Gueret E, Dubois E, Taillandier D, Polge C, Béchet D, Gauquelin-Koch G, Evans A, Arnemo JM, Swenson JE, Blanc S, Simon C, Lefai E, Bertile F, Combaret L. Cells 2021 Jul 23;10(8):1873. doi: 10.3390/cells10081873.